دانلود رایگان مقاله انگلیسی بررسی های (مطالعات) ترکیبی و فعالیت های بیولوژیکی (زیست شناسی) روغن های Perovskia abrotanoides Karel به همراه ترجمه فارسی
|عنوان فارسی مقاله:
|بررسی های (مطالعات) ترکیبی و فعالیت های بیولوژیکی (زیست شناسی) روغن های Perovskia abrotanoides Karel
|عنوان انگلیسی مقاله:
|Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils
|رشته های مرتبط:
|مهندسی کشاورزی، صنایع غذایی، زیست فناوری مواد غذایی، میکروب شناسی مواد غذایی، گیاه پزشکی و گیاهان دارویی
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Background: Current study has been designed to evaluate the chemical composition of essential and fixed oils from stem and leaves of Perovskia abrotanoides and antioxidant and antimicrobial activities of these oils. Results: GC-MS analysis of essential oil identified 19 compounds with (E)-9-dodecenal being the major component in stem and hexadecanoic acid in leaves. In contrast, GC-MS analysis of fixed oil showed 40 constituents with α-amyrin the major component in stem and α-copaene in leaves. The antioxidant activity showed the highest value of 76.7% in essential oil from leaves in comparison with fixed oil from stem (45.9%) through inhibition of peroxidation in linoleic acid system. The antimicrobial assay tested on different microorganisms (e.g. E. coli, S. aureus, B. cereus, Nitrospira, S. epidermis, A. niger, A. flavus and C. albicans) showed the higher inhibition zone at essential oil from leaves (15.2 mm on B. cereus) as compared to fixed oil from stem (8.34 mm on S. aureus) and leaves (11.2 mm on S. aureus). Conclusions: The present study revealed the fact that essential oil analyzed from Perovskia abrotanoides stem and leaves could be a promising source of natural products with potential antioxidant and antimicrobial activities, as compared to fixed oil.
Perovskia abrotanoides (Lamiaceae) locally known as hoosh, visk, brazambal, domou, and gevereh [1-4] is a medicinally important plant found in Baluchistan province and northern areas of Pakistan. The plant is used by local communities for treatment of typhoid, headache, gonorrhea, vomiting, motion, toothache, atherosclerosis, cardiovascular diseases, liver fibrosis, and cough [5-7]. It has sedative, analgesic, antiseptic and cooling effect [5,8,9]. Herbal tea of this plant is used in curing infection problems and painful urination . Some of the pharmacological effects of plant such as antiplasmodial, antiinflammatory and cytotoxic effects have also been reported [11-13]. Its antioxidant performance including heart enhancing and optimized performance as cell toxicity in pathogens, viruses and cancer cells were also reported [5,14]. Essential and fixed oils of Perovskia abrotanoides plays an important role in protection of stored grains and showed to be effective in washing wounds, antiring worm, dermal parasites, anti-fungus and anti-hypoxia [14-17]. Despite its multipurpose usage, little data exists on chemical composition as well as biological activities of this plant. Therefore this study was designed to investigate composition of essential and fixed oil and antioxidant and antimicrobial activities of stem and leaves of Perovskia abrotanoides.
Results and discussion
The diversity of agrogeoclimatic conditions of Pakistan offers the broadest array of flora. This rich floral biodiversity of Pakistan constitutes an impressive pool for ‘natural food and healing’ from which the indigenous communities select ingredients for food and prepare herbal recipes for the treatment, management and control of their various ailments. It is believed that antimicrobials and antioxidants of plant origin are without side effects as compared to synthetic drugs and have an enormous therapeutic potential to heal many infections and diseases. Much of the potential of these botanicals is however still unearthed. In current research, a less explored medicinal plant found in Pakistan has been investigated for compositional studies and biological activities.